![]() |
||||
![]() |
False Assumptions and False Results
It has been shown over and over again that prostate PSA tests show false positives and false negatives. That means the prostate PSA test scores negative results when they are actually positive. And positive when they are actually negative. Is that something we would consider reliable anywhere else? And even more interesting is that PSA (prostate specific antigen) has been found not to be specific to the prostate gland. That is because it is not the only organ that secretes this "specific" antigen. Other Places "Prostate PSA" Is Found Concentrations of prostate specific antigen are also found in amniotic fluid, the urethral glands, normal breast tissue, salivary gland tissue, the endometrium, and even in breast milk!ref: Stanley A Brosman. eMedicine: Prostate Specific Antigen. WebMD. http://www.emedicine.com/med/TOPIC3465.HTM#section~CharacteristicsofProstateSpecificAntigen. Retrieved 2008-05-11. And, the prostate specific antigen shows up in other many other types of cells. This includes cells of ovarian cancer, lung cancer, myeloid leukemia, breast cancer, and sometimes even in normal blood cells! It is definitely NOT specific. And there are other conditions which can also elevate your P.S.A. levels, such as: Infections, benign swelling of the prostate (BPH), over-the-counter drugs like ibuprofen, etc... Even practicing prostate massage too aggressively can raise your levels temporarily. The Horrible Prostate Biopsy The New England Journal of Medicine states: "(the) PSA level test has been found to miss 82 percent of tumors in men under 60, and 65 percent of cancers in older men". Usually, and unfortunately, after a man reads with a high prostate PSA score a prostate biopsy is often requested. Now, get this: Dr. James Eastham (MD, FACS, of Memorial Sloan-Kettering Cancer Center) states: "Only 1 out of 4 biopsys detected cancer that existed." But, prostate biopsies can be very risky and dangerous in themselves. Even the National Cancer Institute and The US Preventative Services Task Force are in opposition to routine prostate PSA testing because they believe the risks of follow-up tests (prostate biopsy) and the treatment side effects may outweigh the possible benefits. Simpler Safer Methods Dr. Garzotto (member of the OHSU Cancer Institute and director of urologic oncology at the PVAMC, associate professor of surgery ((urology)) in the OHSU School of Medicine) who is the lead study investigator states: "Knowing a patient's age and the results of a few simple clinical tests is all the information we need to accurately predict tumor grade without performing a biopsy. It is now well known that men who get low readings might still be harboring dangerous cancers. And men who have high readings might be completely healthy." What The Man Who Discovered Prostate PSA Has To Say This is what Richard J. Ablin (the researcher who discovered the antigen in 1970) has to say about the prostate PSA test:
"...the test is hardly more effective than a coin toss. As I’ve been trying to make clear for many years now, P.S.A. testing can’t detect prostate cancer and, more important,
it can’t distinguish between the two types of prostate cancer
— the one that will kill you and the one that won’t." - RICHARD J. ABLIN - Published: March 9, 2010 What's It All About?? The prostate specific antigen was first identified by researchers who were attempting to find a substance in seminal fluid (semen) that would aid in the investigation of rape cases. ref: Hara M, Inorre T, Fukuyama T. (1971). "Some physicochemical characteristics of gamma-seminoprotein, an antigenic component specific for human seminal plasma". Jpn J Legal Med. 25: 322–324. The substance called "prostate specific antigen" is produced for the ejaculate. In normal healthy life, it has a function . Prostate PSA liquifies the semen and allows sperm to swim freely. ref: Balk SP, Ko YJ, Bubley GJ (January 2003). "Biology of prostate specific antigen". J. Clin. Oncol. 21 (2): 383–91. Prostate PSA is also believed to be necessary in dissolving the cervical mucous cap, which then allows the entry of sperm. ref:American Society of Andrology Handbook. San Francisco, Calif.: American Society of Andrology. ISBN 1891276026. http://www.andrologysociety.com/resources/handbook/ch.8.asp. Retrieved 2006-09-17. The American Study Says: The Prostate PSA Test Did Not Save Lives The results from the American study on PSA shows that over a 7 to 10 year period, PSA screening did not reduce the death rate in men 55 and over. ref: The effect of screening with prostate specific antigen (PSA) testing: The New England Journal of Medicine. http://www.nejm.org/doi/full/10.1056/NEJMoa0810696 According to the America Study the prostate specific antigen tests are not a reliable way of detecting cancer. And according to the European Study, these tests do scare many men into debilitating procedures that are not necessary 95% of the time. ref: The European PSA test study: http://www.nejm.org/doi/full/10.1056/ NEJMoa0810084 That just said: "95% of the time"! Why Not Just Forget About It?! Conclusions: The prostate PSA is a protein that is produced by the prostate gland. It is often elevated in amount in the presence of prostate cancer. BUT, it is also elevated in other prostate disorders and for many other totally unrelated health disorders. And, it seems that the consensus among the medical researchers now is this: Just forget about the prostate PSA tests and their ambiguous "scores" as a screening tool for prostate cancer because they are just so unreliable.
~ William |
|||